TB-500 is a healing & repair research compound currently in stock directly from a verified Chinese manufacturer. Every batch is HPLC-verified and shipped with a Certificate of Analysis (COA). Sourcing is direct — no intermediaries. Minimum order value is $600 USD. International shipping available.
TB-500 (Thymosin Beta-4 Acetate) is a synthetic 43-amino acid polypeptide corresponding to the full sequence of Thymosin Beta-4, a naturally occurring protein found in virtually all mammalian cells and the most abundant G-actin-sequestering protein in eukaryotic cells. Unlike locally-acting peptides, TB-500's primary research interest lies in its systemic distribution and its role in actin regulation — the structural process fundamental to cell migration, differentiation, and tissue remodeling.
Preclinical research in rodent and rodent-based cardiac models has examined TB-500 in contexts including wound closure, ischemia-reperfusion injury recovery, and musculoskeletal injury models. Its mechanism of interest centers on G-actin sequestration and promotion of cellular migration, which distinguishes it from BPC-157's more localized gastroprotective and repair profile.
PeptidesFromChina.co supplies TB-500 as a lyophilized powder in 5mg and 10mg vials, synthesized to 99%+ purity verified by HPLC and Mass Spectrometry. Certificate of Analysis is provided with each batch. All products are intended for laboratory research use only and are not for human consumption.
| Chemical Class | Synthetic polypeptide (actin-binding) |
|---|---|
| Synonyms | Thymosin Beta-4 Acetate, Tβ4, TB4 |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
| Amino Acids | 43 |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular Weight | ~4963 Da |
| CAS Number | 77591-33-4 |
| PubChem CID | 16132341 |
| Research Areas | Systemic tissue recovery, wound healing, cardiac protection, cellular migration, inflammation |
| Form | Lyophilized powder |
| Storage | −20°C long-term; 2-8°C aqueous up to 2 weeks |
| Name | Strength | Pack Size | Purity | Availability | Price (USD) |
|---|---|---|---|---|---|
| TB-500 (Thymosin Beta-4 Acetate) | 2 mg | 10 vials | ≥98% | In Stock | $50.00 |
| TB-500 (Thymosin Beta-4 Acetate) | 5 mg | 10 vials | ≥98% | In Stock | $88.00 |
| TB-500 (Thymosin Beta-4 Acetate) | 10 mg | 10 vials | ≥98% | In Stock | $173.00 |
Testing method: HPLC / LC-MS (["HPLC","LC-MS","Endotoxins","Heavy Metals","Sterility","Water Content","Visible Particulates","Assay","Impurities"]). Every batch is tested before shipment. Purity ≥99% confirmed per batch.
Certificate of Analysis: Manufacturer COA · Simple COA. Documentation is available for every batch sold.
TB-500 has been studied in multiple wound healing models, including full-thickness dermal wound studies in rodents. Research has focused on the compound's apparent acceleration of re-epithelialization and angiogenesis through G-actin sequestration and cellular migration promotion — key processes in tissue remodeling.
Cardiac research represents one of the most studied areas of Thymosin Beta-4 activity. Rodent studies in ischemia-reperfusion injury models have examined its apparent role in cardiomyocyte survival and neovascularization following myocardial infarction, with proposed mechanisms involving actin cytoskeletal regulation and anti-apoptotic signaling.
Rodent models of muscle injury have examined systemic TB-500 administration in contexts of muscle fiber repair and post-injury fibrosis reduction. Research interest in this area is driven by the compound's systemic distribution profile, which differentiates it from locally-acting repair peptides like BPC-157.
TB-500 is available in 5mg and 10mg vials as lyophilized powder. Wholesale format, minimum 10 vials per box.
TB-500 acts systemically via G-actin sequestration and is studied for cardiac protection and broad musculoskeletal recovery. BPC-157 acts more locally and is studied for gut protection and tendon/ligament repair. Frequently studied in combination — see Wolverine Blend.
TB-500 is synthesized to 99%+ purity, verified by HPLC and Mass Spectrometry. Certificate of Analysis from the originating facility is included with every batch.
Lyophilized TB-500 should be stored at −20°C, away from light and moisture. Aqueous solutions should be kept at 2-8°C and used within 2 weeks.
For laboratory research use only. Not for human or veterinary use. PeptidesFromChina.co is a B2B wholesale supplier operating under strict research-use-only terms. All products are sold exclusively for in vitro and preclinical research purposes.