GHK-Cu is a skin & hair research compound currently in stock directly from a verified Chinese manufacturer. Every batch is HPLC-verified and shipped with a Certificate of Analysis (COA). Sourcing is direct — no intermediaries. Minimum order value is $600 USD. International shipping available.
GHK-Cu (Glycyl-L-Histidyl-L-Lysine copper(II)) is a naturally occurring copper chelating tripeptide first isolated from human plasma by Loren Pickart in 1973. The complex consists of the tripeptide GHK (Gly-His-Lys) coordinated to a copper(II) ion — a configuration that enables cellular uptake via copper chelation and interaction with a broad range of extracellular matrix and intracellular receptors. Plasma concentrations of GHK-Cu decline significantly with age: from approximately 200 ng/mL at age 20 to under 80 ng/mL by age 60, making it a subject of regenerative biology and aging research.
Preclinical and in vitro research has examined GHK-Cu's influence on fibroblast proliferation, collagen and glycosaminoglycan synthesis, matrix metalloproteinase regulation, wound remodeling, and stem cell gene expression. Its small molecular size and copper-chelating structure enable tissue penetration that larger peptides cannot achieve.
PeptidesFromChina.co supplies GHK-Cu as a lyophilized powder, synthesized to 99%+ purity and verified by HPLC and Mass Spectrometry. Certificate of Analysis is provided with each batch. All products are intended for laboratory research use only and are not for human consumption.
| Chemical Class | Copper chelating tripeptide |
|---|---|
| Synonyms | Copper Tripeptide-1, Copper Peptide, GHK:Cu |
| Sequence | Gly-His-Lys (copper(II) complex) |
| Molecular Formula | C₁₄H₂₃CuN₆O₄ |
| Molecular Weight | 403.9 Da |
| CAS Number | 49557-75-7 |
| PubChem CID | 73587 |
| Research Areas | Wound healing, collagen synthesis, skin repair, hair follicle biology, antioxidant, DNA repair, anti-inflammatory |
| Form | Lyophilized powder |
| Storage | 2-8°C short-term; −20°C long-term; protect from light |
| Name | Strength | Pack Size | Purity | Availability | Price (USD) |
|---|---|---|---|---|---|
| GHK-Cu | 50 mg | 10 vials | ≥98% | In Stock | $32.00 |
| GHK-Cu | 100 mg | 10 vials | ≥98% | In Stock | $57.00 |
Testing method: HPLC / LC-MS (["HPLC","LC-MS","Sterility","Water Content","Heavy Metals","Endotoxins","Visible Particulates","Assay","Impurities","Microbiology"]). Every batch is tested before shipment. Purity ≥99% confirmed per batch.
Certificate of Analysis: Manufacturer COA · Simple COA. Documentation is available for every batch sold.
The majority of GHK-Cu research involves skin biology and extracellular matrix remodeling. In vitro studies have demonstrated stimulation of collagen, elastin, and glycosaminoglycan synthesis in fibroblast cultures. Animal wound models have shown accelerated wound contraction and dermis regeneration. GHK-Cu's influence on matrix metalloproteinase regulation and DNA repair mechanisms are particular research foci.
GHK-Cu has been studied in the context of hair follicle biology, including follicle enlargement and potential prolongation of the anagen (growth) phase in animal and in vitro models. This has made it a subject of dermatological research on androgenic alopecia and hair follicle cycling at the cellular level.
GHK-Cu demonstrates superoxide dismutase-mimetic antioxidant activity in vitro and has been shown to modulate expression of multiple anti-inflammatory genes. It has been proposed as an endogenous regulator of inflammation through copper-mediated redox signaling and has been investigated for its role in stem cell gene expression modulation.
GHK-Cu is supplied as lyophilized powder. Contact us for current vial sizes and availability.
Yes. Research-grade GHK-Cu is a lyophilized powder at 99%+ purity with COA documentation. Cosmetic-grade formulations contain GHK-Cu as an ingredient in a carrier solution at lower and variable concentrations without batch-level purity verification.
99%+ purity verified by HPLC and Mass Spectrometry. Certificate of Analysis from the originating facility is included with every batch.
Lyophilized GHK-Cu: store at −20°C long-term, 2-8°C for short-term use. Protect from light and humidity. Aqueous solutions: use within 1-2 weeks, keep refrigerated.
For laboratory research use only. Not for human or veterinary use. PeptidesFromChina.co is a B2B wholesale supplier operating under strict research-use-only terms. All products are sold exclusively for in vitro and preclinical research purposes.