Oxytocin Acetate is a hormonal regulation research compound currently in stock directly from a verified Chinese manufacturer. Every batch is HPLC-verified and shipped with a Certificate of Analysis (COA). Sourcing is direct — no intermediaries. Minimum order value is $600 USD. International shipping available.
Oxytocin is a cyclic nonapeptide neurohormone synthesized in the hypothalamus (paraventricular and supraoptic nuclei) and released from the posterior pituitary. Its structure — a six-residue disulfide-bonded ring (Cys¹-Cys⁶) with a three-residue C-terminal tail — is shared with the vasopressin/oxytocin peptide family. Oxytocin acetate is the acetic acid salt form used for research, providing enhanced aqueous stability compared to the free base. Research interest encompasses oxytocin's roles in social behavior, pair bonding, maternal behavior, anxiety modulation, and peripheral effects including uterine contractility and lactation.
CNS oxytocin research has expanded substantially beyond its classical roles in parturition and lactation. Studies in rodent models have examined oxytocin's effects on social recognition memory, fear extinction, aggression reduction, and reward circuitry modulation — primarily via the oxytocin receptor (OXTR) expressed in amygdala, hippocampus, nucleus accumbens, and prefrontal cortex. Research in autism spectrum disorder (ASD) models has used oxytocin as a pharmacological probe for studying social deficit phenotypes. Peripheral oxytocin research includes its role in metabolic regulation — OXTR is expressed in adipose tissue, and rodent studies have examined oxytocin's apparent role in energy homeostasis.
PeptidesFromChina.co supplies oxytocin acetate as a lyophilized powder at 99%+ purity, verified by HPLC and Mass Spectrometry. Certificate of Analysis accompanies every batch. All products are for laboratory research use only and are not for human consumption.
| Chemical Class | Cyclic nonapeptide neurohormone (acetate salt) |
|---|---|
| Synonyms | Oxytocin acetate, OT, Ocytocin |
| Sequence | Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH₂ (Cys¹-Cys⁶ disulfide) |
| Amino Acids | 9 |
| Molecular Weight | 1007.2 Da |
| CAS Number | 50-56-6 |
| Receptor Target | OXTR (oxytocin receptor); weak V1a/V2 cross-reactivity |
| Research Areas | Social behavior neuroscience, anxiety/fear research, maternal behavior, metabolic regulation, uterine pharmacology |
| Form | Lyophilized powder (acetate salt) |
| Storage | −20°C long-term; 2-8°C aqueous (short-term) |
| Molecular Formula | C₄₃H₆₆N₁₂O₁₂S₂ (disulfide form) |
| Name | Strength | Pack Size | Purity | Availability | Price (USD) |
|---|---|---|---|---|---|
| Oxytocin Acetate | 5 mg | 10 vials | ≥98% | In Stock | $50.00 |
| Oxytocin Acetate | 10 mg | 10 vials | ≥98% | In Stock | $107.00 |
Testing method: HPLC / LC-MS (["HPLC","LC-MS","Endotoxins","Water Content","Assay"]). Every batch is tested before shipment. Purity ≥99% confirmed per batch.
Certificate of Analysis: Manufacturer COA. Documentation is available for every batch sold.
Rodent research has established oxytocin as a key modulator of pro-social behavior via OXTR signaling in the amygdala, nucleus accumbens, and prefrontal cortex. Studies have examined oxytocin's effects on social recognition memory, partner preference, separation anxiety, and aggression in both conventional and social defeat models. Oxytocin serves as the reference compound for studies investigating the neurochemical basis of social bonding and its disruption in psychiatric disease models.
Research has examined oxytocin's anxiolytic properties — particularly its suppression of amygdala fear responses via OXTR-mediated inhibition of CeA (central amygdala) neurons. Fear extinction paradigms using intra-amygdala oxytocin infusion in rodents have contributed to understanding of how oxytocin modulates fear memory consolidation and extinction. These studies position oxytocin as a pharmacological tool in anxiety and PTSD model research.
Beyond CNS effects, oxytocin receptor expression in adipose tissue, pancreatic β-cells, and adrenal glands has generated research interest in peripheral oxytocin signaling. Rodent studies have examined oxytocin's apparent effects on food intake, fat mass, and glucose metabolism — a phenotype consistent with OXTR expression in hypothalamic energy-sensing circuits. The peripheral metabolic effects of oxytocin represent an emerging area of research distinct from its classical reproductive and social neuroscience roles.
Oxytocin and vasopressin share a near-identical structure (differing at positions 3 and 8) and have overlapping receptor affinities. Oxytocin preferentially binds OXTR; vasopressin preferentially binds V1a, V1b, and V2 receptors. In research, they are distinguished by receptor selectivity: oxytocin is preferred when studying social behavior and OXTR signaling; vasopressin for water balance (V2), vascular tone (V1a), and stress axis (V1b).
Rodent ASD models (Shank3 knockout, CNTNAP2 knockout, valproate-exposed, oxytocin receptor-null mice) show social deficit phenotypes. Oxytocin administration has been used as a pharmacological probe to determine whether OXTR activation can reverse social deficits in these models — providing insight into whether the oxytocin system is a viable target in ASD neuroscience research.
Oxytocin acetate is synthesized to 99%+ purity, verified by HPLC and Mass Spectrometry. Certificate of Analysis from the manufacturing facility is included with every batch.
Lyophilized oxytocin acetate should be stored at −20°C. Aqueous solutions should be kept at 2-8°C and used within 2 weeks. The disulfide bond can be susceptible to oxidative degradation — avoid metal contamination and use dilute acetic acid (0.1%) for reconstitution if water solubility is insufficient.
For laboratory research use only. Not for human or veterinary use. PeptidesFromChina.co is a B2B wholesale supplier operating under strict research-use-only terms. All products are sold exclusively for in vitro and preclinical research purposes.