KLOW Fragment is a healing & repair research compound currently in stock directly from a verified Chinese manufacturer. Every batch is tested by the manufacturer for purity and concentration as part of routine quality control. Sourcing is direct — no intermediaries. Minimum order value is $600 USD. International shipping available.
KLOW Fragment is a pre-mixed lyophilized research formulation containing TB-500 Fragment (17-24), BPC-157, KPV (Lys-Pro-Val), and GHK-Cu (copper peptide). It is the Fragment-based counterpart to KLOW (which uses full-length TB-500/Thymosin Beta-4 Acetate). The substitution of TB-500 Fragment for the full 43-amino acid Tβ4 isolates the actin-binding domain contribution in the four-component combination.
Each component contributes a defined mechanistic layer: TB-500 Fragment provides actin-dependent cell migration via the LKKT G-actin sequestration motif; BPC-157 drives angiogenesis and growth factor receptor sensitization; KPV (the C-terminal tripeptide of α-MSH) suppresses NF-κB nuclear translocation and reduces inflammatory cytokine production; GHK-Cu promotes collagen synthesis, MMP regulation, and antioxidant gene expression. The combination covers cell migration, vascularization, anti-inflammatory signaling, and ECM remodeling in a four-pathway approach to tissue repair research.
PeptidesFromChina.co supplies KLOW Fragment as a lyophilized powder with each component individually purity-verified at ≥98% by HPLC before blending. For laboratory research use only.
| Components | TB-500 Fragment (17-24) + BPC-157 + KPV + GHK-Cu |
|---|---|
| Vs. KLOW | Fragment version uses TB-500 Frag (17-24) in place of full-length TB-500 (43aa Tβ4) |
| Vs. GLOW Fragment | KLOW Fragment = GLOW Fragment + KPV (NF-κB anti-inflammatory layer) |
| Research Areas | Tissue repair, anti-inflammatory models, dermal/mucosal biology, ECM remodeling, actin-mediated migration |
| Form | Lyophilized powder blend |
| Storage | −20°C long-term; 2-8°C aqueous solution |
| Sequence | N/A — complex blend |
| CAS Number | N/A — complex blend |
| Molecular Formula | N/A — complex blend |
| Molecular Weight | N/A — complex blend |
| Name | Strength | Pack Size | Purity | Availability | Price (USD) |
|---|---|---|---|---|---|
| KLOW Fragment | 80 mg | 10 vials | ≥98% | In Stock | $156.00 |
Testing method: HPLC / LC-MS. Every batch is tested before shipment. Purity ≥99% confirmed per batch.
Every batch is tested by the manufacturer for purity and concentration as part of routine quality control, using methods such as HPLC and LC-MS. These results are kept in the manufacturer's internal quality-control records and are not issued as a separate certificate or document.
KPV's NF-κB suppression is the mechanistic differentiator between KLOW Fragment and GLOW Fragment. In chronic wound and hypertrophic scar models — where persistent NF-κB-driven inflammation impairs transition to the proliferative repair phase — KPV is the targeted anti-inflammatory component. Research examines the four-component combination in macrophage (RAW264.7, THP-1) cytokine secretion assays alongside fibroblast migration (TB-500 Fragment contribution) and endothelial tube formation (BPC-157 contribution) to characterise the combined inflammatory and repair pharmacology.
Side-by-side comparison of KLOW Fragment versus KLOW (full TB-500) allows researchers to isolate the actin-binding domain contribution within the four-component combination. Endpoints across cell migration, angiogenesis, cytokine suppression, and collagen synthesis can be measured simultaneously to assess whether the Fragment provides equivalent outcomes to the full-length Tβ4 in the context of concurrent KPV anti-inflammatory activity.
KLOW contains TB-500 (full 43-amino acid Thymosin Beta-4 Acetate), BPC-157, KPV, and GHK-Cu. KLOW Fragment substitutes TB-500 Fragment (17-24) — the isolated actin-binding octapeptide of Tβ4 — for the full-length peptide. In both formulations, KPV provides the NF-κB anti-inflammatory layer that differentiates KLOW from GLOW. The choice between Fragment and full-length versions is driven by whether the research design requires the complete Tβ4 biology or specifically the actin-binding domain activity.
GLOW Fragment contains TB-500 Fragment, BPC-157, and GHK-Cu. KLOW Fragment adds KPV (Lys-Pro-Val) — the α-MSH-derived anti-inflammatory tripeptide that suppresses NF-κB signaling and inflammatory cytokine production. KLOW Fragment is selected for research models where inflammation is a co-pathology alongside impaired repair: chronic wounds, inflammatory mucosal disease, or conditions where excessive NF-κB activity impairs the proliferative phase of healing.
Each component (TB-500 Fragment, BPC-157, KPV, GHK-Cu) is individually purity-verified at ≥98% by HPLC before blending. Identity is confirmed by mass spectrometry. Every batch is tested by the manufacturer as part of routine quality control.
For laboratory research use only. Not for human or veterinary use. PeptidesFromChina.co is a B2B wholesale supplier operating under strict research-use-only terms. All products are sold exclusively for in vitro and preclinical research purposes.